[HTML][HTML] Involvement of the mitochondrial pathway in cold storage and rewarming-associated apoptosis of human renal proximal tubular cells
AK Salahudeen, H Huang, M Joshi, NA Moore… - American journal of …, 2003 - Elsevier
The cellular and molecular mechanisms of cold storage-ATN are not well characterized. In
our earlier studies, cold storage caused necrosis of human proximal tubular epithelial
(RPTE) cells, whereas apoptosis was prominent during rewarming. An intriguing finding was
the pronounced swelling of the mitochondria in the cold, which promoted us to further
characterize its role in rewarming-associated apoptosis. Human proximal tubular epithelial
cells were cold stored in University of Wisconsin (UW) solution for 48 h followed by 24 h of …
our earlier studies, cold storage caused necrosis of human proximal tubular epithelial
(RPTE) cells, whereas apoptosis was prominent during rewarming. An intriguing finding was
the pronounced swelling of the mitochondria in the cold, which promoted us to further
characterize its role in rewarming-associated apoptosis. Human proximal tubular epithelial
cells were cold stored in University of Wisconsin (UW) solution for 48 h followed by 24 h of …
