Expression and function of semaphorin 3A and its receptors in human monocyte-derived macrophages

JD Ji, KH Park-Min, LB Ivashkiv - Human immunology, 2009 - Elsevier
Semaphorins are a large family of secreted and membrane-bound proteins. Recently,
several roles of semaphorins in the immune system have emerged. Several semaphorins
and their receptors are expressed in a variety of lymphoid and myeloid cells and affect
immune cell functions, including cell proliferation, differentiation, chemotaxis, and cytokine
production. However, the roles of class 3 semaphorins in human myeloid cells are not well
known. Here we examined the regulation of expression of class 3 semaphorins and their …