During normal aging, there is a decline in all physiological functions in the organism. One of
the most affected organs is the brain, where neurons lose their proper synaptic function
leading to cognitive impairment. Aging is one of the main risk factors for the development of
neurodegenerative diseases, such as Alzheimer's disease. One of the main responsible
factors for synaptic dysfunction in aging and neurodegenerative diseases is the
accumulation of abnormal proteins forming aggregates. The most studied brain aggregates …