[HTML][HTML] Looking beyond respiratory cultures: microbiome-cytokine signatures of bacterial pneumonia and tracheobronchitis in lung transplant recipients
J Shankar, MH Nguyen, MM Crespo, EJ Kwak… - American Journal of …, 2016 - Elsevier
Bacterial pneumonia and tracheobronchitis are diagnosed frequently following lung
transplantation. The diseases share clinical signs of inflammation and are often difficult to
differentiate based on culture results. Microbiome and host immune-response signatures
that distinguish between pneumonia and tracheobronchitis are undefined. Using a
retrospective study design, we selected 49 bronchoalveolar lavage fluid samples from 16
lung transplant recipients associated with pneumonia (n= 8), tracheobronchitis (n= 12) or …
transplantation. The diseases share clinical signs of inflammation and are often difficult to
differentiate based on culture results. Microbiome and host immune-response signatures
that distinguish between pneumonia and tracheobronchitis are undefined. Using a
retrospective study design, we selected 49 bronchoalveolar lavage fluid samples from 16
lung transplant recipients associated with pneumonia (n= 8), tracheobronchitis (n= 12) or …
