[HTML][HTML] Impact of allograft injury time of onset on the development of chronic lung allograft dysfunction after lung transplantation
MY Shino, SS Weigt, N Li, A Derhovanessian… - American Journal of …, 2017 - Elsevier
The impact of allograft injury time of onset on the risk of chronic lung allograft dysfunction
(CLAD) remains unknown. We hypothesized that episodes of late-onset (≥ 6 months)
allograft injury would produce an augmented CXCR3/ligand immune response, leading to
increased CLAD. In a retrospective single-center study, 1894 transbronchial biopsy samples
from 441 lung transplant recipients were reviewed for the presence of acute rejection (AR),
lymphocytic bronchiolitis (LB), diffuse alveolar damage (DAD), and organizing pneumonia …
(CLAD) remains unknown. We hypothesized that episodes of late-onset (≥ 6 months)
allograft injury would produce an augmented CXCR3/ligand immune response, leading to
increased CLAD. In a retrospective single-center study, 1894 transbronchial biopsy samples
from 441 lung transplant recipients were reviewed for the presence of acute rejection (AR),
lymphocytic bronchiolitis (LB), diffuse alveolar damage (DAD), and organizing pneumonia …
