[HTML][HTML] The rectal mucosa and condomless receptive anal intercourse in HIV-negative MSM: implications for HIV transmission and prevention

CF Kelley, CS Kraft, TJ De Man, C Duphare, HW Lee… - Mucosal …, 2017 - Elsevier
Most HIV transmissions among men who have sex with men (MSM), the group that
accounted for 67% of new US infections in 2014, occur via exposure to the rectal mucosa.
However, it is unclear how the act of condomless receptive anal intercourse (CRAI) may
alter the mucosal immune environment in HIV-negative MSM. Here, we performed a
comprehensive characterization of the rectal mucosal immune environment for the
phenotype and production of pro-inflammatory cytokines by CD4 and CD8 T cells, global …